About bats and COVID-19 by Heliana Dundarova

Heliana Dundarova, PhD, an expert in bat studies; a scientist at IBER-BAS (Bulgaria) and a guest researcher at Osh State University (Kyrgyzstan) during field work

Bats (order Chiroptera) are the second largest order of mammals (1411 species). They are the only mammals capable of flying actively, which allowed them to be globally distributed. In general, flight has led to high refinement of order Chiroptera, and orientation through echolocation, which allows them navigate in reduced visibility environments. In-flight body temperature rises, which speeds up their metabolism and puts their bodies in a constant state of high fever. The temperature varies from 38 to 41 °C. This type of energy production and consumption is huge and intolerable for other mammals. High energy potential leads to the release of huge amount of free radicals, which damage DNA molecules and kill the cells of mammals. However, this does not happen to bats and scientists have found out why. They have a mutation which accelerates the cell’s ability to find and repair damaged DNA molecules. In addition, their cellular mechanism practically does not allow the damaged cells to multiply, as is the case with all other mammals, and cancer is rare.

The colony of Rhinolophus lepidus in the mine

In all mammals, the immune system triggers a group of signaling proteins called interferons. When a virus enters a cell, interferons produce signals to warn the other cells to activate their antiviral mechanism and prevent the virus from further multiplying. In bats, interferons are constantly activated and there is no mechanism to switch them off and thus they constantly control the viruses. Therefore, extreme energy production, high body temperature, mechanisms for the rapid recovery of damaged DNA, and the specific immune system make bats a suitable reservoir of different types of RNA viruses. These viruses are adapted to the dynamic cellular life of their hosts as well as to bats. RNA viruses from bats cannot be transmitted directly to humans because their fine-tuning requires other organisms (intermediate hosts) in which the cells viruses adapt to the final host. Similar examples from the recent past are SARS-CoV coronaviruses and the MERS-CoV virus. In 2002, SARS-CoV caused Severe Acute Respiratory Syndrome (SARS) and has affected about 30 countries, of which, for 800 people, the outcome was lethal. It is established that similar coronaviruses are carried from bats but the infection to people did not happen directly. The source of the infection is civets, a species of rare predator that is sold freely to markets in China. The virus has long been spread by the intermediate host in Chinese markets.

In 2012, the Middle East Respiratory Syndrome (MERS) appeared. The intermediate hosts are camels, who have been carrying the coronavirus for about 30 years. MERS caused an epidemic in the Arabian Peninsula, about 2000 people were infected, and the death rate was 50%. The scenario for the SARS-CoV-2 virus, which causes the COVID-19 syndrome, is similar. The virus genome is most similar to the CoV RaTG13 coronavirus known from the intermediate horseshoe bat (Rhinolophus affinis), which inhabits the Yunnan province, China and Southeast Asia. The virus binding receptor at the intermediate horseshoe bat and other horseshoe bats cannot directly bind to the human ACE2 receptor located on the outside of the lung cells. There was a tuning time (mutation) period in the intermediate host that took years to separate SARS-CoV-2.

The Horseshoe Bat – Rhinolophus ferrumequinum

Globally, mammalian organisms, including humans, are full of different corona-viruses. They are divided into specific groups, and interspecific transmission is extremely rare, since the virus must adapt to the specific cellular receptor of the final host. Therefore, direct transmission from bat to human with SARS-CoV-2 is excluded.

Bats are the natural “biopesticides” on Earth. Globally, one bat consumes a huge amount of the known pests on forests and farmlands such as the insect pests on coniferous plantations, cereals and fruit orchards. Bats regulate the numbers of the Greater Wax Moth; whose larvae are parasites on beehives.

The Lesser Mouse-eared Bat – Myotis blythii – species widely distributed in Eurasia

Many bat species control the mosquito populations, which are the main reservoir and vector of Zika, Yellow fever and Dengue. One bat colony can eat about 100 tons of insects per night.

The danger does not come from bats or other animals, but from the human beings. People penetrate into previously virgin places, destroy natural habitats at unimaginable speeds, and move quickly from one to another point of the world. All this allows pathogens to overcome the interspecies barriers that previously prevented them from emerge and spill-over uncontrollably.

References:

Simmons N. B. 2005. Order Chiroptera. In: Wilson, D. E., Reeder, D. M., editors. Mammal species of the world: a taxonomic and geographic reference. 3rd ed. Baltimore (MD): The Johns Hopkins University Press. p. 312-52

Kristian G. Andersen, Andrew Rambaut, W. Ian Lipkin, Edward C. Holmes, Robert F. Garry. The proximal origin of SARS-CoV-2. Nature Medicine, 2020; https://doi.org/10.1038/s41591-020-0820-9

Zhou, P., Yang, X., Wang, X. et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 2020; https://doi.org/10.1038/s41586-020-2012-7

Ji, W., Wang, W., Zhao, X., Za, J., Li, X. Cross-species transmission of the newly identified coronavirus 2019-nCoV. Journal of Medical Virology, 2020; https://doi.org/10.1002/jmv.25682

Mountains of Central Asia as a touristic destination by Sergey Toropov

Summer day in the mountains of Kyrgyzstan
Mountains around Chon-Kemin River, Kyrgyzstan

The majestic mountain systems of Dzhungar, Tien Shan and Pamir-Alai, ridges covered with dazzling white glaciers, and emerald meadows of mountain valleys with sapphire eyes of lakes, seething streams and waterfalls of fast mountain rivers carrying their crystal waters into deserts, languishing from the heat. All this diversity of ecological landscapes and climatic zones is the “Mecca” for tourists, scientists and travelers to Central Asia!

Issyk-Kul Lake is one of the largest mountain lakes in the world

Summer in mountains of Kyrgyzstan

Abandoned field before rain

Such a variety of natural landscapes creates unique conditions for the numerous representatives of the animal world, including many insects, the vivid representatives of which are butterflies – natural flowers of nature. More than 300 species of diurnal butterflies live in various ecosystems of Central Asia. Attracting magnets of this region are species such as swallowtails Parnassius loxias, an inhabitant of the rocky canyons of the Central Tien Shan in the Sary-Jaz river basin, and Parnassius autocrator, which is the dream of any lepidopterologist, the inhabitant of screes among the rocky massifs of the Pamirs. The habitats of these two species of Apollo butterflies are very local and almost inaccessible. In 2006, the entomological world was shocked by a sensation. In the unexplored places of the Inner Tien Shan, in the system of the Moldo-Too ridge, a new species of Apollo was described by the Russian entomologist S. Churkin. It was named as Parnassius davydovi. This is the first such discovery in a hundred years.

Papilio apollo merzbacheri, Kichi-Kemin, Kyrgyzstan

In addition to the 18 species of Apollos, occurring in this region, 14 species of “sulphurs” butterflies (Colias) are of particular interest to travelers – entomologists. Not one region of the world has such a diversity of species of this genus. Entomologists can find in the region the carrot-scarlet Colias draconis, an inhabitant of the steppe slopes of the Western Tien Shan, and the scarlet fiery red Colias regia, the endemic of Tien Shan. Other species include unusually painted in the ash-brown tones Colias christophi helialaica is an inhabitant of the Alai mountain range, persistently closed by fogs and the legendary, very rare Colias erschoffi, an inhabitant of the harsh middle mountains of the Dzhungar Range.

The fiery red blue-butterfly from Lycaenidae family –  Thersamonia solskyi attila – inhabits the mountain systems of eastern Alai. Endemic blues Plebejus lycaenidae with brilliant eyes on the lower wings inhabit buckthorn bushes along the banks of mountain rivers. Numerous species from satyr family – Hyponephele, Pseudochazara, Chazara, Karanasa and other satyrs inhabit dry foothills and high mountain steppes of various ranges.

All this sparkling and shimmering in the sun variety of diurnal butterflies cannot leave indifferent ecological tourists, entomologists and respectable scientists who are happy to plunge into the world of butterflies, during visits of Central Asia.

And when the daytime colors fade, the more modestly colored representatives of the night butterflies begin to dance near the daylight lamps. These are the nimble owlet moths (Noctuidae) with interesting genus Cuculia and swift hawk-moths with a rare species of Rhethera komarovi, and of course the peacock-eyed Neoris that amazes everyone with their large eye-spots on wings. Brightly colored tiger-moths inhabit high mountain valleys. Almost all species of this group of butterflies are endemic to Central Asia, including such genera and species as Oroncus, Acerbia, Arctia ruckbeili and numerous representatives of Palearctia genus.

This natural variety of mountain landscapes is inhabited by 318 breeding bird species. Besides, another 108 bird species appear in the region during migrations and wintering. Many birdwatchers have been attracted to the region by opportunity to observe such species as Ibisbill (Ibidorhyncha struthersii), an inhabitant of pebble floodplains of high mountain rivers. Other species of particular interest are a large Bearded Vulture or Lammergeier (Gypaetus barbatus hemachalanus), with a wingspan of about three meters, which makes nests in niches of inaccessible cliffs, and tiny White-browed Tit-warbler (Leptopoecile sophiae) with sapphire plumage, a small inhabitant of juniper dwarf. During trip to mountain valleys tourists will have chance to spot the cautious Pallas’s Sandgrouse (Syrrhaptes paradoxus), nesting in rocky deserts along the shores of the beautiful Issyk-Kul Lake, a rare high-altitude bird Lesser Sand Plover (Charadrius mongolus pamirensis), alpine White-winged Snowfinch (Montifringilla nivalis alpicola), flashing when flying with snow-white wings, and the legendary Blue Whistling Thrush (Myophonus caeruleus turcestanicus), with an amazing flute song, competing with the roar of the waterfall.

Posing rufous-naped tit
Rufous-naped Tit
Bright male of white-browed tit-warbler
White-browed Tit-warbler

Of the 86 species of mammals that live in Kyrgyzstan, the most famous is the fabulous Snow Leopard (Uncia uncia), a resident of rocky gorges. Snow leopards prey on unsurpassed mountain climbers – Ibexes (Capra sibirica), with horns reaches one-and-a-half-meter size. The Marco Polo Argali (Ovis ammon polii) also occur in high mountain valleys, whose horns are also not small. In older males, the length of the horn can reach 165 centimeters. A very beautiful and rare Pallas’s cat (Otocolobus manul) also lives on the alpine wet meadows (“syrts”).

Preparing to hunt...
Least Weasel (Mustela nivalis) in Kegety, Kyrgyzstan

Regional Center of Expertise – Kyrgyzstan – by Chinara Sadykova

The Regional Center of Expertise, Kyrgyzstan was acknowledged on May 31, 2007 by United Nations University (Tokyo, Japan) and since that time it is listed in Global RCE Networking among 168 RCEs around the world  www.rcenetwork.org . On June 26, 2011, the RCE Kyrgyzstan was officially registered by the Ministry of Judges of Kyrgyz Republic as a Public Association of Regional Centers of Expertise on Education for sustainable development the “RCE KG”.The main goal of RCE-KG is “a Promotion of education for sustainable development in Kyrgyzstan”.  From 2007 to present RCE-KG has implemented number of projects supported by  UNESCO Kazakhstan National Office, US Embassy in the Kyrgyz Republic, EURASIA Foundation in Kyrgyzstan Republic, HELVETAS Swiss Inter-cooperation, US State Department, USAID and others.

The RCE-KG cooperates with various stakeholders and partners, including  Kyryz State University named after I. Arabaev, State Agency on Environmental Protection of KG, Ministry of Education of KG, State Patent Department of KG, State Agency on Technical and Vocational Education, Bishkek Humanitarian University, Kyrgyz State University, Kyrgyz Pedagogical University, Kyrgyz Republic Children/Youth Environmental and Tourism Center, Ozone Center. The RCE Kyrgyzstan has sufficient experience of work with local communities and local people from Kyrgyzstan, Uzbekistan and Tajikistan due to several transboundary projects, which were carried out in the Fergana Valley.

The RCE-KG developed training workshops for promotion sustainable principles in daily life, including Training Manual for Sustainable Development at local level.  The RCE also prepared the training module for educators in high education system of Kyrgyzstan for introducing goals and principles of education for sustainable development. The NGO also carried out 10 training workshops in seven region of the Republic.

The RCE is focused on awareness raising and knowledge sharing, including implemented project on “Research of the Structure of traditional knowledge and sustainable management of Kyrgyz social and natural environment”, supported by US Embassy in Kyrgyzstan . The RCE-KG tries to analyze  and connect the historic ethnic culture of Kyrgyz people, relevant to sustainable use of natural elements and local traditional knowledge of recovery and rehabilitation of natural resources. The traditional knowledge and historic social organization of local economy (including livestock grazing in the various mountain belts during a year) could provide some useful solutions for environmental management to ensure sustainable development for future generations.  

At present, the members of RCE-KG are actively involved in several initiatives, working with partners from Kyrgyzstan and other countries to raise funds for projects relevant to environmental education, public awareness and integration of sustainable development principles in everyday life on local, national and regional levels.  

The Persian Leopard in Kazakhstan: new observations

Landscapes of Ustyurt Biosphere Nature Reserve provide good conditions for surviving of wildlife, adapted to arid environment

New fact of Persian Leopard observation in Kazakhstan was confirmed in May 2020 due to camera-trap video taken in Ustyurt Biosphere Nature Reserve.   You can find here the short video about Leopard in the reserve:

The Leopard – Panthera pardus – is included on the IUCN international red list as a vulnerable species (VU) .  The Persian Leopard – P. p. saxicolor or P.p. ciscaucasica is a Central-Asian subspecies. It is even more rare and globally endangered (EN). The range of this species covers the Caucasus Mountains (eastern Turkey, southern Russia, Azerbaijan, Armenia, and Georgia). It is also found in Iraq, northern Iran, Afghanistan, Turkmenistan, and Uzbekistan.

Until recent, the Persian Leopard did not occur in Kazakhstan. It was known from southern Turkmenistan, mostly from Kopetdag and Badkhyz Mountains. Besides, it was found in southern Uzbekistan and Tajikistan. But to the end of XX century, the leopard was almost extinct in both these countries. The distance from Kopetdag Nature Reserve in Turkmenistan to Usyurt Nature Reserve in Kazakhstan is 600 km, and from Badkhyz Nature Reserve to Usyurt Nature Reserve is around 1,000 km (976 km). Leopards needed to cross deserts and populated areas that to reach Kazakhstan. It is surprising that it could happen relatively recently – during last decades. 

First reports about findings and observation of Persian Leopard in Kazakhstan looked anecdotical. Time to time shepherds and people living in remote areas reported about observation of large spotted cat, which they called “kaplon” (the name of large cats, like, for example, cheetah). The leopard was not even included in the list of Kazakhstan fauna. However, in 2007 and 2015, the presence of leopard in Kazakhstan was confirmed by skins of two large cats. Shepherds shot the first leopard in the Mangystau region and showed its skin. Another leopard was captured in a trap set for wolves and also killed. More recently, during fall 2018, an alive leopard was fixed on a camera-trap set in the Ustyurt State Nature Reserve in the framework of the project for feeding scavengers (vultures), conducted with the support of the Rufford Foundation.

Cinereous vultures found scavenge. Photo by Mark Pestov

The leopard is not even officially included in the list of of the fauna of vertebrate animals in Kazakhstan.  Accordingly, this species is not listed in the  Red Book of Republic, which provides legal protection status for rare, vulnerable and endangered species. The last findings allow to make the necessary amendments in Kazakhstan that will provide both legislative and territorial protection of the leopard in the country.

Photo of leopard from camera-trap in Ustyurt Biosphere Nature Reserve

Not only leopard, but the presence of other interesting fauna was confirmed due to projects, organized last years, and camera-traps placed in the valleys of Ustyurt. Other interesting animals, found there, are the grey wolf, Central-Asian caracal, goitered gazelle and many others, adapted to severe conditions of life in arid environment.

Mr. Zhaskayrat Nurmukhambetov,  Deputy Director of the Ustyurt State Nature Reserve and coordinator of the project on feeding of scavengers can provide additional information about this finding.

Studies of fauna in remote corners of Central Asia should be continued and more likely that more secrets of wildlife adaptation and resilience will be discovered in the future.